{"id":8664,"date":"2023-06-03T14:38:37","date_gmt":"2023-06-03T07:38:37","guid":{"rendered":"https:\/\/43hr.com\/?p=8664"},"modified":"2023-06-03T14:38:37","modified_gmt":"2023-06-03T07:38:37","slug":"loai-khang-sinh-moi-voi-cong-nghe-ai-co-the-diet-sieu-vi-khuan-nguy-hiem","status":"publish","type":"post","link":"https:\/\/43hr.com\/loai-khang-sinh-moi-voi-cong-nghe-ai-co-the-diet-sieu-vi-khuan-nguy-hiem\/","title":{"rendered":"Lo\u1ea1i kh\u00e1ng sinh m\u1edbi v\u1edbi c\u00f4ng ngh\u1ec7 AI c\u00f3 th\u1ec3 di\u1ec7t si\u00eau vi khu\u1ea9n nguy hi\u1ec3m"},"content":{"rendered":"
Nh\u1edd s\u1eed d\u1ee5ng tr\u00ed tu\u1ec7 nh\u00e2n t\u1ea1o (AI), c\u00e1c nh\u00e0 nghi\u00ean c\u1ee9u \u0111\u00e3 t\u00ecm ra m\u1ed9t lo\u1ea1i kh\u00e1ng sinh m\u1edbi c\u00f3 t\u00e1c d\u1ee5ng ch\u1ed1ng l\u1ea1i vi khu\u1ea9n kh\u00e1ng thu\u1ed1c \u0111\u1eb7c bi\u1ec7t nguy hi\u1ec3m. Lo\u1ea1i si\u00eau vi khu\u1ea9n kh\u00e1ng thu\u1ed1c n\u00e0y th\u01b0\u1eddng g\u00e2y ra nhi\u1ec5m tr\u00f9ng \u0111\u01b0\u1eddng h\u00f4 h\u1ea5p v\u00e0 nhi\u1ec5m tr\u00f9ng m\u00e1u kh\u00f3 ch\u1eefa t\u1ea1i c\u00e1c b\u1ec7nh vi\u1ec7n.<\/p>\n
Khi th\u1eed nghi\u1ec7m tr\u00ean da c\u1ee7a nh\u1eefng con chu\u1ed9t b\u1ecb nhi\u1ec5m\u00a0si\u00eau vi khu\u1ea9n, lo\u1ea1i\u00a0kh\u00e1ng sinh\u00a0n\u00e0y \u0111\u00e3 ki\u1ec3m so\u00e1t s\u1ef1 ph\u00e1t tri\u1ec3n c\u1ee7a vi khu\u1ea9n, m\u1edf ra ti\u1ec1m n\u0103ng m\u1edbi trong \u1ee9ng d\u1ee5ng\u00a0AI\u00a0\u0111\u1ec3 t\u1ea1o ra thu\u1ed1c ph\u00f9 h\u1ee3p ch\u1ed1ng l\u1ea1i m\u1ea7m b\u1ec7nh kh\u00e1ng thu\u1ed1c.<\/p>\n
H\u1ee3p ch\u1ea5t \u0111\u01b0\u1ee3c AI x\u00e1c \u0111\u1ecbnh ho\u1ea1t \u0111\u1ed9ng theo c\u00e1ch ch\u1ec9 ng\u0103n ch\u1eb7n m\u1ea7m b\u1ec7nh nh\u01b0ng kh\u00f4ng di\u1ec7t c\u00e1c vi khu\u1ea9n c\u00f3 l\u1ee3i s\u1ed1ng trong ru\u1ed9t ho\u1eb7c tr\u00ean da, nh\u1edd \u0111\u00f3 m\u00e0 t\u1ea1o n\u00ean kh\u00e1ng sinh tr\u00fang \u0111\u00edch (thu h\u1eb9p ph\u1ea1m vi) hi\u1ebfm g\u1eb7p. Theo c\u00e1c nh\u00e0 nghi\u00ean c\u1ee9u, n\u1ebfu nhi\u1ec1u lo\u1ea1i kh\u00e1ng sinh c\u00f3 th\u1ec3 ho\u1ea1t \u0111\u1ed9ng ch\u00ednh x\u00e1c nh\u01b0 v\u1eady, \u0111\u00e3 c\u00f3 th\u1ec3 ng\u0103n ng\u1eeba t\u00ecnh tr\u1ea1ng\u00a0vi khu\u1ea9n kh\u00e1ng thu\u1ed1c\u00a0ngay t\u1eeb \u0111\u1ea7u.<\/p>\n
Nghi\u00ean c\u1ee9u \u0111\u01b0\u1ee3c c\u00f4ng b\u1ed1 tr\u00ean t\u1ea1p ch\u00ed sinh h\u00f3a h\u1ecdc Nature Chemical Biology.<\/p>\n
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TS. Cesar de la Fuente – Tr\u01b0\u1eddng Y khoa Perlman, \u0110\u1ea1i h\u1ecdc Pennsylvania nh\u1eadn \u0111\u1ecbnh ph\u01b0\u01a1ng ph\u00e1p n\u00e0y r\u1ea5t h\u1ee9a h\u1eb9n. B\u1ea3n th\u00e2n TS. Cesar de la Fuente m\u1eb7c d\u00f9 kh\u00f4ng tham gia v\u00e0o nghi\u00ean c\u1ee9u tr\u00ean nh\u01b0ng l\u00e0 chuy\u00ean gia \u0111ang s\u1eed d\u1ee5ng AI \u0111\u1ec3 t\u00ecm ra c\u00e1c ph\u01b0\u01a1ng ph\u00e1p \u0111i\u1ec1u tr\u1ecb m\u1edbi.<\/p>\n
TS. Cesar de la Fuente cho bi\u1ebft, ph\u01b0\u01a1ng ph\u00e1p t\u00ecm ki\u1ebfm thu\u1ed1c m\u1edbi n\u00e0y l\u00e0 m\u1ed9t l\u0129nh v\u1ef1c m\u1edbi n\u1ed5i m\u00e0 c\u00e1c nh\u00e0 nghi\u00ean c\u1ee9u \u0111\u00e3 th\u1eed nghi\u1ec7m t\u1eeb kho\u1ea3ng n\u0103m 2018. C\u00f4ng ngh\u1ec7 AI gi\u00fap t\u00ecm ra lo\u1ea1i thu\u1ed1c m\u1edbi gi\u1ea3m \u0111\u00e1ng k\u1ec3 th\u1eddi gian c\u1ea7n thi\u1ebft \u0111\u1ec3 ph\u00e2n lo\u1ea1i h\u00e0ng ngh\u00ecn h\u1ee3p ch\u1ea5t \u0111\u1ea7y h\u1ee9a h\u1eb9n.<\/p>\n
“Tr\u00ed tu\u1ec7 nh\u00e2n t\u1ea1o (AI), nh\u01b0 ch\u00fang ta \u0111\u00e3 th\u1ea5y c\u00f3 th\u1ec3 \u0111\u01b0\u1ee3c \u00e1p d\u1ee5ng th\u00e0nh c\u00f4ng trong nhi\u1ec1u l\u0129nh v\u1ef1c. T\u00ecm ra thu\u1ed1c m\u1edbi l\u1ea1i l\u00e0 m\u1ed9t “chi\u1ebfn tuy\u1ebfn” ti\u1ebfp theo c\u1ee7a AI”, chuy\u00ean gia n\u00e0y b\u1eadt m\u00ed.<\/p>\n
Trong nghi\u00ean c\u1ee9u tr\u00ean, c\u00e1c nh\u00e0 khoa h\u1ecdc t\u1eadp trung v\u00e0o si\u00eau vi khu\u1ea9n Actinetobacter baumanii. Hi\u1ec7n nay, lo\u1ea1i si\u00eau vi khu\u1ea9n kh\u00e1ng thu\u1ed1c nguy hi\u1ec3m n\u00e0y \u0111ang ho\u00e0nh h\u00e0nh t\u1ea1i c\u00e1c b\u1ec7nh vi\u1ec7n v\u00e0 c\u00e1c c\u01a1 s\u1edf ch\u0103m s\u00f3c s\u1ee9c kh\u1ecfe. Si\u00eau vi khu\u1ea9n n\u00e0y d\u1ec5 l\u00e2y lan do c\u00f3 th\u1ec3 b\u00e1m d\u00ednh v\u00e0o c\u00e1c b\u1ec1 m\u1eb7t nh\u01b0 tay n\u1eafm c\u1eeda v\u00e0 tr\u00ean m\u1eb7t b\u00e0n, m\u1eb7t qu\u1ea7y.<\/p>\n
Do b\u00e1m l\u1ea5y c\u00e1c ph\u00e2n \u0111o\u1ea1n DNA t\u1eeb c\u00e1c sinh v\u1eadt m\u00e0 si\u00eau vi khu\u1ea9n ti\u1ebfp x\u00fac \u0111\u1ec3 ti\u1ebfn h\u00f3a, Actinetobacter baumanii c\u00f3 th\u1ec3 kh\u00e1ng thu\u1ed1c \u0111i\u1ec1u tr\u1ecb. V\u00ec th\u1ebf, si\u00eau vi khu\u1ea9n n\u00e0y c\u00f3 th\u1ec3 g\u00e2y nhi\u1ec5m \u0111\u01b0\u1eddng h\u00f4 h\u1ea5p,\u00a0nhi\u1ec5m tr\u00f9ng\u00a0m\u00e1u ho\u1eb7c nhi\u1ec5m tr\u00f9ng da kh\u00f3 ch\u1eefa.<\/p>\n
CDC M\u1ef9 t\u1eebng tuy\u00ean b\u1ed1 v\u00e0o n\u0103m 2019 r\u1eb1ng lo\u1ea1i nhi\u1ec5m tr\u00f9ng c\u1ea7n nh\u1ea5t c\u00e1c lo\u1ea1i kh\u00e1ng sinh m\u1edbi \u0111\u1ec3 \u0111i\u1ec1u tr\u1ecb ch\u00ednh l\u00e0 si\u00eau vi khu\u1ea9n Acinetobacter baumanii kh\u00e1ng thu\u1ed1c.<\/p>\n
M\u1ed9t nghi\u00ean c\u1ee9u g\u1ea7n \u0111\u00e2y \u1edf c\u00e1c b\u1ec7nh nh\u00e2n nh\u1eadp vi\u1ec7n do nhi\u1ec5m tr\u00f9ng Acinetobacter baumanii cho th\u1ea5y, si\u00eau vi khu\u1ea9n n\u00e0y kh\u00e1ng thu\u1ed1c ngay c\u1ea3 \u0111\u1ed1i v\u1edbi d\u00f2ng kh\u00e1ng sinh carbapenem m\u1ea1nh. H\u1eadu qu\u1ea3 l\u00e0, c\u1ee9 4 ng\u01b0\u1eddi th\u00ec c\u00f3 1 ng\u01b0\u1eddi t\u1eed vong trong v\u00f2ng 1 th\u00e1ng sau khi \u0111\u01b0\u1ee3c ch\u1ea9n \u0111o\u00e1n nhi\u1ec5m tr\u00f9ng.<\/p>\n
Trong nghi\u00ean c\u1ee9u m\u1edbi n\u00e0y, nh\u00e0 khoa h\u1ecdc y sinh Jon Stokes (\u0110\u1ea1i h\u1ecdc McMaster \u1edf Hamilton, Ontario, Canada) c\u00f9ng c\u00e1c nh\u00e0 nghi\u00ean c\u1ee9u t\u1eeb Vi\u1ec7n Broad (Tr\u01b0\u1eddng C\u00f4ng ngh\u1ec7\u00a0Massachusetts) v\u00e0 \u0110H Harvard \u0111\u00e3 s\u1eed d\u1ee5ng k\u1ef9 thu\u1eadt s\u00e0ng l\u1ecdc thu\u1ed1c th\u00f4ng l\u01b0\u1ee3ng cao.<\/p>\n
Sau nhi\u1ec1u tu\u1ea7n \u0111\u1ec3 vi khu\u1ea9n\u00a0Acinetobacter baumanii ti\u1ebfp x\u00fac v\u1edbi h\u01a1n 7.500 t\u00e1c nh\u00e2n, thu\u1ed1c v\u00e0 th\u00e0nh ph\u1ea7n ho\u1ea1t ch\u1ea5t c\u1ee7a thu\u1ed1c, c\u00e1c nh\u00e0 khoa h\u1ecdc \u0111\u00e3 t\u00ecm th\u1ea5y 480 h\u1ee3p ch\u1ea5t ng\u0103n ch\u1eb7n s\u1ef1 ph\u00e1t tri\u1ec3n c\u1ee7a vi khu\u1ea9n.<\/p>\n
Th\u00f4ng tin tr\u00ean \u0111\u01b0\u1ee3c \u0111\u01b0a v\u00e0o m\u00e1y t\u00ednh \u0111\u1ec3 t\u1ea1o n\u00ean thu\u1eadt to\u00e1n tr\u00ed tu\u1ec7 nh\u00e2n t\u1ea1o (AI). Trong v\u00f2ng v\u00e0i gi\u1edd, AI \u0111\u00e3 s\u00e0ng l\u1ecdc m\u00f4 h\u00ecnh h\u01a1n 6.000 ph\u00e2n t\u1eed, thu h\u1eb9p ph\u1ea1m vi t\u00ecm ki\u1ebfm xu\u1ed1ng c\u00f2n 240 h\u1ee3p ch\u1ea5t \u0111\u00e3 th\u1eed nghi\u1ec7m trong ph\u00f2ng th\u00ed nghi\u1ec7m, t\u1eeb \u0111\u00f3 r\u00fat xu\u1ed1ng th\u00e0nh 9 h\u1ee3p ch\u1ea5t \u1ee9c ch\u1ebf vi khu\u1ea9n t\u1ed1t nh\u1ea5t.<\/p>\n
\u0110i\u1ec1u \u0111\u1eb7c bi\u1ec7t m\u00e0 c\u00e1c nh\u00e0 khoa h\u1ecdc ph\u00e1t hi\u1ec7n th\u1ea5y ch\u00ednh l\u00e0 h\u1ee3p ch\u1ea5t RS102895 ban \u0111\u1ea7u \u0111\u01b0\u1ee3c ph\u00e1t tri\u1ec3n nh\u01b0 m\u1ed9t ph\u01b0\u01a1ng ph\u00e1p \u0111i\u1ec1u tr\u1ecb ti\u1ec1m n\u0103ng cho b\u1ec7nh ti\u1ec3u \u0111\u01b0\u1eddng.<\/p>\n
Nh\u00e0 khoa h\u1ecdc Jon Stokes nh\u1eadn th\u1ea5y r\u1eb1ng, h\u1ee3p ch\u1ea5t RS102895 d\u01b0\u1eddng nh\u01b0 ho\u1ea1t \u0111\u1ed9ng theo c\u00e1ch ho\u00e0n to\u00e0n m\u1edbi nh\u1edd ng\u0103n ch\u1eb7n c\u00e1c th\u00e0nh ph\u1ea7n c\u1ee7a vi khu\u1ea9n di chuy\u1ec3n t\u1eeb b\u00ean trong t\u1ebf b\u00e0o ra ngo\u00e0i b\u1ec1 m\u1eb7t.<\/p>\n
\u201c\u0110\u00e2y l\u00e0 m\u1ed9t c\u01a1 ch\u1ebf di\u1ec7t vi khu\u1ea9n kh\u00e1 th\u00fa v\u1ecb, ch\u01b0a t\u1eebng th\u1ea5y \u1edf c\u00e1c lo\u1ea1i thu\u1ed1c kh\u00e1ng sinh l\u00e2m s\u00e0ng cho \u0111\u1ebfn nay m\u00e0 t\u00f4i bi\u1ebft”, nh\u00e0 khoa h\u1ecdc Jon Stokes n\u00f3i. H\u01a1n n\u1eefa, RS102895 \u2013 m\u00e0 c\u00e1c nh\u00e0 nghi\u00ean c\u1ee9u \u0111\u1ed5i t\u00ean th\u00e0nh abaucin \u2013 ch\u1ec9 ho\u1ea1t \u0111\u1ed9ng tr\u00ean vi khu\u1ea9n Actinetobacter baumanii.<\/p>\n
Chuy\u00ean gia v\u1ec1 h\u00f3a sinh n\u00e0y cho bi\u1ebft, h\u1ea7u h\u1ebft c\u00e1c lo\u1ea1i kh\u00e1ng sinh \u0111\u1ec1u l\u00e0 t\u00e1c nh\u00e2n ph\u1ed5 r\u1ed9ng, c\u00f3 t\u00e1c d\u1ee5ng ch\u1ed1ng l\u1ea1i nhi\u1ec1u lo\u00e0i vi khu\u1ea9n. Thu\u1ed1c kh\u00e1ng sinh ph\u1ed5 r\u1ed9ng g\u00e2y \u00e1p l\u1ef1c ch\u1ecdn l\u1ecdc l\u00ean nhi\u1ec1u lo\u1ea1i vi khu\u1ea9n, khi\u1ebfn nhi\u1ec1u lo\u1ea1i nhanh ch\u00f3ng ti\u1ebfn h\u00f3a v\u00e0 chia s\u1ebb gene gi\u00fap ch\u00fang kh\u00e1ng thu\u1ed1c v\u00e0 t\u1ed3n t\u1ea1i. V\u1edbi lo\u1ea1i thu\u1ed1c m\u1edbi n\u00e0y, do ch\u1ee7 y\u1ebfu ch\u1ec9 di\u1ec7t vi khu\u1ea9n Actinetobacter n\u00ean s\u1ebd h\u1ea1n ch\u1ebf t\u00ecnh tr\u1ea1ng lan truy\u1ec1n kh\u00e1ng thu\u1ed1c.<\/p>\n
Theo CNN Health<\/em><\/p>\n","protected":false},"excerpt":{"rendered":" Nh\u1edd s\u1eed d\u1ee5ng tr\u00ed tu\u1ec7 nh\u00e2n t\u1ea1o (AI), c\u00e1c nh\u00e0 nghi\u00ean c\u1ee9u \u0111\u00e3 t\u00ecm ra m\u1ed9t lo\u1ea1i kh\u00e1ng sinh m\u1edbi c\u00f3 t\u00e1c d\u1ee5ng ch\u1ed1ng l\u1ea1i vi khu\u1ea9n kh\u00e1ng thu\u1ed1c \u0111\u1eb7c bi\u1ec7t nguy hi\u1ec3m. Lo\u1ea1i si\u00eau vi khu\u1ea9n kh\u00e1ng thu\u1ed1c n\u00e0y…<\/p>\n","protected":false},"author":11,"featured_media":8665,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[26],"tags":[],"yoast_head":"\n